SCHEMBL5568231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5568069	0.86	JAK2 (0.56)	EGFRFADS1LCKTTBK1TTBK2
	SCHEMBL9017044	0.86	EGFR (0.68)	EGFRFADS1LCKTTBK1TTBK2
	SCHEMBL5564578	0.85	MAPT (0.55)	EGFRFADS1LCKERBB2MAPT
	SCHEMBL5565322	0.85	AURKA (0.52)	EGFRFADS1LCKERBB2MAPT
	Hydrochloric Acid SCHEMBL11091908	0.84	EGFR (0.68)	EGFRFADS1LCKTTBK1TTBK2
	SCHEMBL5569470	0.84	EGFR (0.58)	EGFRTTBK1TTBK2ERBB2KDM4E
	SCHEMBL4787336	0.83	EGFR (0.64)	EGFRFADS1LCKTTBK1TTBK2
	SCHEMBL5569425	0.83	EGFR (0.72)	EGFRERBB2MAPK1FBP1
	SCHEMBL5569119	0.82	TP53 (0.50)	EGFRFADS1LCKMAPTTP53
	SCHEMBL17532922	0.81	EGFR (0.72)	EGFRFADS1LCKERBB2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.