Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928436 | 0.87 | CNR1 (0.49) | PTGER1CNR1CNR2HCAR3HCAR2 | |
| SCHEMBL20461114 | 0.84 | CNR1 (0.45) | PTGER1CNR1CNR2HCAR3HCAR2 | |
| SCHEMBL1234393 | 0.81 | PTGER1 (0.40) | PTGER1CNR1CNR2HCAR3HCAR2 | |
| SCHEMBL1233694 | 0.80 | PTGER1 (0.39) | PTGER1CNR1CNR2HCAR3HCAR2 | |
| SCHEMBL1234199 | 0.80 | PTGER1 (0.39) | PTGER1CNR1CNR2HCAR3HCAR2 | |
| SCHEMBL11365648 | 0.78 | HCAR2 (0.49) | PTGER1CNR1CNR2HCAR3HCAR2 | |
| SCHEMBL1232628 | 0.78 | PTGER1 (0.45) | PTGER1CNR1CNR2HCAR3SMPD1 | |
| SCHEMBL1234136 | 0.77 | CNR1 (0.36) | PTGER1CNR1CNR2L3MBTL1SMPD1 | |
| SCHEMBL1233607 | 0.77 | PTGER1 (0.35) | PTGER1HCAR3HCAR2KDM4EMEN1 | |
| SCHEMBL27740912 | 0.76 | KDM4E (0.51) | PTGER1CNR1CNR2HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863809-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107753-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-10-12 | — | — | WO | disclosed |