Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563792 | 1.00 | SCN9A (0.37) | SCN9AP2RX7ACE | |
| 2,2,2-Trifluoroethanaminium SCHEMBL8207820 | 0.96 | SCN9A (0.35) | SCN9AP2RX7ACE | |
| Trifluoroacetamide SCHEMBL8207815 | 0.96 | SCN9A (0.35) | SCN9AP2RX7ACE | |
| SCHEMBL5563163 | 0.92 | HDAC8 (0.37) | SCN9A | |
| SCHEMBL5566971 | 0.90 | HDAC8 (0.42) | — | |
| SCHEMBL5568646 | 0.90 | HDAC8 (0.42) | — | |
| SCHEMBL5568361 | 0.86 | ACE (0.40) | ACE | |
| SCHEMBL5568606 | 0.85 | HDAC8 (0.44) | ACE | |
| SCHEMBL5563160 | 0.85 | HDAC8 (0.44) | ACE | |
| SCHEMBL5563362 | 0.85 | MC4R (0.42) | SCN9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-B1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2007-11-07 | — | — | EP | disclosed |
| US-6335360-B1 | INDOLINE-2-CARBOXYLIC AMIDE DERIVATIVES; OBESITY, EATING AND PSYCHOLOGICAL DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-01 | — | — | US | disclosed |