Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464055 | 0.78 | TP53 (0.40) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL284728 | 0.78 | TSHR (0.40) | ALDH1A1TP53TSHRSLC7A5 | |
| SCHEMBL13502522 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL9527915 | 0.76 | TSHR (0.38) | ALDH1A1TP53TSHRSLC7A5 | |
| SCHEMBL10953833 | 0.74 | TP53 (0.36) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| Ethylene SCHEMBL28195307 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TP53TSHRSLC7A5 | |
| SCHEMBL10953837 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TP53TSHR | |
| SCHEMBL7326571 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL2784566 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TP53TSHRMAPTPTGS1 | |
| SCHEMBL209810 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458661-B1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE SRL (IT) | 2007-05-02 | — | — | EP | claimed |
| US-7067690-B2 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2006-06-27 | — | — | US | claimed |
| US-20050171379-A1 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-08-04 | — | — | US | claimed |
| EP-1458661-A1 | SEPARATION OF DIASTEREOISOMERS | Basell Poliolefine Italia S.p.A. (IT) | 2004-09-22 | — | — | EP | claimed |
| WO-2003055831-A1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-07-10 | — | — | WO | claimed |
| EP-1458661-B1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE SRL (IT) | 2007-05-02 | — | — | EP | disclosed |
| US-7067690-B2 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2006-06-27 | — | — | US | disclosed |
| US-20050171379-A1 | Separation of diastereoisomers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-08-04 | — | — | US | disclosed |
| EP-1458661-A1 | SEPARATION OF DIASTEREOISOMERS | Basell Poliolefine Italia S.p.A. (IT) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055831-A1 | SEPARATION OF DIASTEREOISOMERS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171379-A1 | Separation of diastereoisomers | SSB, C9, CA1 | ALDH1A1 691/4885TP53 1954/4885TSHR 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.