Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17270494 | 1.00 | KDM4E (0.41) | KDM4EPKMGRIN2BGRIN2CMEN1 | |
| SCHEMBL17270495 | 1.00 | KDM4E (0.41) | KDM4EPKMGRIN2BGRIN2CMEN1 | |
| SCHEMBL15848401 | 0.91 | KMT2A (0.39) | GRIN2BGRIN2CMEN1KMT2AGPR119 | |
| SCHEMBL17270449 | 0.91 | KMT2A (0.39) | GRIN2BGRIN2CMEN1KMT2AGPR119 | |
| SCHEMBL17270481 | 0.90 | GPR119 (0.36) | GRIN2BGRIN2CMEN1KMT2ATSHR | |
| SCHEMBL15848546 | 0.90 | MEN1 (0.40) | GRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL17270510 | 0.90 | KMT2A (0.47) | GRIN2BGRIN2CMEN1KMT2ATSHR | |
| SCHEMBL15848435 | 0.90 | GPR119 (0.36) | GRIN2BGRIN2CMEN1KMT2ATSHR | |
| SCHEMBL15848631 | 0.90 | MEN1 (0.40) | GRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL15848280 | 0.90 | KMT2A (0.47) | GRIN2BGRIN2CMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786806-A1 | DPP-IV INHIBITORS | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005121131-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2005-12-22 | — | — | WO | disclosed |