Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 6/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12620733 | 0.86 | MAP4K4 (0.43) | HTTCDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL5066798 | 0.80 | HTT (0.42) | HTTCDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL252899 | 0.78 | LRRK2 (0.40) | HTTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL243905 | 0.78 | LRRK2 (0.40) | HTTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL252871 | 0.78 | LRRK2 (0.40) | HTTSMN1; SMN2LMNATP53TSHR | |
| SCHEMBL30479201 | 0.78 | HTT (0.59) | HTTCDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL8826207 | 0.78 | HTT (0.59) | HTTCDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL22524173 | 0.77 | LMNA (0.44) | CDK1CCNB1CCNB2CCNB3SMN1; SMN2 | |
| SCHEMBL150046 | 0.77 | CYP1A2 (0.55) | UTS2RHTTCDK1CCNB1CCNB2 | |
| SCHEMBL251552 | 0.76 | PDE1B (0.43) | HTTCDK1SMN1; SMN2MAP4K4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1596806-A4 | COMPOSITIONS AND METHODS FOR TREATING CANCER USING IGSF9 AND LIV-1 | BIOGEN IDEC INC (US) | 2007-08-29 | — | — | EP | disclosed |
| US-20070071674-A1 | Polynucleotides encoding novel isoforms of IGSF9 | MCLACHLAN KAREN | 2007-03-29 | — | — | US | disclosed |
| EP-1596806-A2 | COMPOSITIONS AND METHODS FOR TREATING CANCER USING IGSF9 AND LIV-1 | Biogen Idec MA Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20040258616-A1 | Compositions and methods for treating cancer using IGSF9 and LIV-1 | IDEC PHARMACEUTICALS CORPORATION | 2004-12-23 | — | — | US | disclosed |
| WO-2004066933-A2 | COMPOSITIONS AND METHODS FOR TREATING CANCER USING IGSF9 AND LIV-1 | BIOGEN IDEC MA INC. (US) | 2004-08-12 | — | — | WO | disclosed |
| US-6166198-A | Methods for oligonucleotide synthesis | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2000-12-26 | — | — | US | disclosed |