Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426030 | 0.89 | F10 (0.45) | MAPK14F10MAPK13MAPK12MAPK11 | |
| SCHEMBL3428575 | 0.71 | F10 (0.48) | MAPK14F10MAPK13MAPK12MAPK11 | |
| SCHEMBL3428811 | 0.70 | F10 (0.41) | F10 | |
| SCHEMBL3424592 | 0.68 | F10 (0.77) | MAPK14F10MAPK13MAPK12MAPK11 | |
| SCHEMBL3428639 | 0.66 | F10 (0.47) | MAPK14F10 | |
| SCHEMBL3426427 | 0.66 | MAPK14 (0.39) | MAPK14F10MAPK13MAPK12MAPK11 | |
| SCHEMBL6454562 | 0.65 | F10 (0.40) | F10 | |
| SCHEMBL3428572 | 0.65 | F10 (0.47) | MAPK14F10 | |
| SCHEMBL3426176 | 0.64 | CA12 (0.36) | F10 | |
| SCHEMBL3427642 | 0.63 | F10 (0.49) | MAPK14F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748996-A1 | SUBSTITUTED THIOPHEN-CARBOXYLIC ACID AMIDES, THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A DRUG | Boehringer Ingelheim International GmbH (DE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005111014-A1 | SUBSTITUTED THIOPHEN-CARBOXYLIC ACID AMIDES, THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A DRUG | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |