SCHEMBL5569231

SCHEMBL5569231

CCOc1ccccc1CNC(=O)Cc1cccc(CC(C)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 19/20 1.00
ADRB3 P13945 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5037110 1.00 ADRB2 (1.00) ADRB2ADRB3
SCHEMBL5037108 1.00 ADRB2 (1.00) ADRB2ADRB3
SCHEMBL5034319 0.94 ADRB2 (0.89) ADRB2ADRB3
SCHEMBL5034328 0.94 ADRB2 (0.89) ADRB2ADRB3
SCHEMBL5037158 0.93 ADRB2 (1.00) ADRB2ADRB3
SCHEMBL5037163 0.93 ADRB2 (1.00) ADRB2ADRB3
SCHEMBL5041917 0.88 ADRB2 (1.00) ADRB2ADRB3
SCHEMBL5041910 0.88 ADRB2 (1.00) ADRB2ADRB3
SCHEMBL5034372 0.87 ADRB2 (0.84) ADRB2ADRB3
SCHEMBL5034367 0.87 ADRB2 (0.84) ADRB2ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1708992-B1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LTD (GB) 2007-08-08 EP disclosed