Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569371 | 0.93 | EGFR (0.60) | EGFRERBB2 | |
| SCHEMBL5564700 | 0.79 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL29623598 | 0.79 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL185131 | 0.79 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL1333601 | 0.76 | EGFR (0.80) | EGFRERBB2 | |
| SCHEMBL5569255 | 0.76 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL5568779 | 0.75 | EGFR (0.50) | EGFRERBB2 | |
| SCHEMBL5564555 | 0.75 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL3126409 | 0.74 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL14205852 | 0.74 | EGFR (0.78) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032508-A1 | Quinazoline derivatives as tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032508-A1 | Quinazoline derivatives as tyrosine kinase inhibitors | ABL1, ERBB2, LCK | EGFR 15/4885ERBB2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.