Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274094 | 0.84 | CHRM2 (0.40) | ATMDPP4DPP8DPP9 | |
| SCHEMBL3243618 | 0.84 | CHRM2 (0.40) | ATMDPP4DPP8DPP9 | |
| SCHEMBL143131 | 0.77 | ATM (0.44) | ATMRIPK1DPP4DPP8DPP9 | |
| SCHEMBL20973810 | 0.75 | ATM (0.43) | ATMRIPK1DPP4DPP8DPP9 | |
| SCHEMBL20973146 | 0.75 | ATM (0.43) | ATMRIPK1DPP4DPP8DPP9 | |
| SCHEMBL585463 | 0.73 | CHRM2 (0.41) | — | |
| SCHEMBL584822 | 0.73 | CHRM2 (0.41) | — | |
| SCHEMBL15988125 | 0.73 | CHRM2 (0.38) | DPP4DPP8DPP9PIK3CD | |
| SCHEMBL3248189 | 0.71 | NR1H2 (0.34) | — | |
| SCHEMBL22367025 | 0.71 | PARP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615878-A4 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-1615878-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004064730-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-08-05 | — | — | WO | disclosed |