Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865008 | 0.79 | ALDH1A1 (0.70) | ALDH1A1CYP2D6L3MBTL1HDAC3HDAC4 | |
| SCHEMBL21307662 | 0.77 | HDAC3 (0.71) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL13680173 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1CDC25BKMT2A | |
| SCHEMBL1557559 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1KMT2ALMNA | |
| SCHEMBL264585 | 0.76 | CA12 (0.52) | ALDH1A1CYP2D6HDAC3HDAC4HDAC1 | |
| SCHEMBL27493267 | 0.76 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1KMT2AMAPT | |
| SCHEMBL18123060 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CYP2D6L3MBTL1MAPK1CDC25B | |
| SCHEMBL11613274 | 0.76 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1CDC25BKMT2A | |
| SCHEMBL5702002 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CYP2D6L3MBTL1HDAC3HDAC4 | |
| SCHEMBL8337268 | 0.74 | PPID (0.58) | ALDH1A1L3MBTL1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417151-B1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | UNIV GRENOBLE 1 (FR) | 2016-09-14 | — | — | EP | disclosed |
| EP-2417151-B1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | UNIV GRENOBLE 1 (FR) | 2016-09-14 | — | — | EP | disclosed |
| US-9133237-B2 | Cyclic peptides with an anti-parasitic activity | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2015-09-15 | — | — | US | disclosed |
| US-9133237-B2 | Cyclic peptides with an anti-parasitic activity | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2015-09-15 | — | — | US | disclosed |
| US-9133237-B2 | Cyclic peptides with an anti-parasitic activity | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2015-09-15 | — | — | US | disclosed |
| EP-2417151-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | Universite Joseph Fourier (Grenoble 1) (FR) | 2012-02-15 | — | — | EP | disclosed |
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-09 | — | — | US | disclosed |
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-09 | — | — | US | disclosed |
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010116085-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010116085-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | VIP, NGLY1, QPCT | ALDH1A1 4453/4885CYP2D6 4293/4885L3MBTL1 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.