Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786986 | 0.96 | DPP4 (0.53) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL4740069 | 0.78 | DPP4 (0.49) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL5569869 | 0.75 | DPP4 (0.45) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL5569872 | 0.75 | DPP4 (0.45) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL4784332 | 0.74 | CPT1A (0.51) | DPP4DPP8DPP9DPP7GRM5 | |
| Trifluoroacetic Acid SCHEMBL19974982 | 0.72 | DPP4 (0.43) | DPP4DPP8DPP9DPP7GRM5 | |
| Trifluoroacetic Acid SCHEMBL19974984 | 0.72 | DPP4 (0.43) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL2050644 | 0.72 | GRM5 (0.61) | GRM5 | |
| SCHEMBL17654626 | 0.71 | NR1H4 (0.60) | GRM5 | |
| SCHEMBL17654623 | 0.71 | NR1H4 (0.60) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786806-A1 | DPP-IV INHIBITORS | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005121131-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2005-12-22 | — | — | WO | disclosed |