Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549972 | 1.00 | HSD11B1 (0.36) | HSD11B1RIPK1SCN9ANPY5R | |
| SCHEMBL2697829 | 1.00 | HSD11B1 (0.36) | HSD11B1RIPK1SCN9ANPY5R | |
| SCHEMBL2697824 | 1.00 | HSD11B1 (0.36) | HSD11B1RIPK1SCN9ANPY5R | |
| SCHEMBL549971 | 1.00 | HSD11B1 (0.36) | HSD11B1RIPK1SCN9ANPY5R | |
| SCHEMBL5630592 | 0.90 | HSD11B1 (0.37) | HSD11B1RIPK1SCN9ANPY5R | |
| SCHEMBL5630597 | 0.90 | HSD11B1 (0.37) | HSD11B1RIPK1SCN9ANPY5R | |
| SCHEMBL2699309 | 0.85 | HSD11B1 (0.36) | HSD11B1RIPK1NPY5R | |
| SCHEMBL2699862 | 0.85 | HSD11B1 (0.36) | HSD11B1RIPK1NPY5R | |
| SCHEMBL550783 | 0.85 | HSD11B1 (0.36) | HSD11B1RIPK1NPY5R | |
| SCHEMBL550782 | 0.85 | HSD11B1 (0.36) | HSD11B1RIPK1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053024-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-05-18 | — | — | WO | disclosed |