Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567510 | 0.79 | AAK1 (0.50) | P2RY1MAPTAAK1ALDH1A1 | |
| SCHEMBL5570412 | 0.79 | P2RY1 (0.46) | P2RY1HTR1ES1PR3MEN1LMNA | |
| SCHEMBL17727263 | 0.79 | F10 (0.61) | F10F2MEN1MAPTKMT2A | |
| SCHEMBL5644384 | 0.78 | GRM4 (0.46) | F10F2FPR2P2RY1MEN1 | |
| SCHEMBL5644386 | 0.78 | F10 (0.44) | F10F2FPR2P2RY1MEN1 | |
| SCHEMBL5569392 | 0.77 | CHEK1 (0.49) | P2RY1S1PR3AAK1 | |
| SCHEMBL5566711 | 0.76 | MAPT (0.44) | FPR2P2RY1HTR1ES1PR3MEN1 | |
| SCHEMBL5569380 | 0.76 | P2RY1 (0.43) | F10F2FPR2P2RY1MEN1 | |
| SCHEMBL6714054 | 0.73 | HTR1E (0.62) | HTR1ES1PR3MEN1MAPTKMT2A | |
| SCHEMBL29069770 | 0.73 | EPHX1 (0.59) | HTR1ES1PR3MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250415-B2 | 1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, β-aminoacids, α-aminoacids and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-31 | — | — | US | disclosed |