Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565920 | 0.75 | MEN1 (0.39) | GAA | |
| SCHEMBL5568649 | 0.71 | CES1 (0.37) | — | |
| SCHEMBL7002280 | 0.64 | GAA (0.34) | GAASMN1; SMN2CDC25B | |
| SCHEMBL7001476 | 0.64 | GAA (0.34) | GAASMN1; SMN2CDC25B | |
| SCHEMBL5565090 | 0.63 | BRD4 (0.31) | — | |
| SCHEMBL1760720 | 0.62 | TSHR (0.50) | GAACDC25B | |
| SCHEMBL28303303 | 0.60 | CDC25B (0.43) | GAACDC25B | |
| SCHEMBL25202453 | 0.59 | CDC25B (0.48) | GAACDC25B | |
| SCHEMBL30635627 | 0.59 | CDC25B (0.48) | GAACDC25B | |
| SCHEMBL10373066 | 0.59 | BRD4 (0.46) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750719-A2 | TREATMENT OF DISEASES ASSOCIATED WITH ALTERED LEVEL OF AMYLOID BETA PEPTIDES | Boehringer Ingelheim International GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110422-A2 | TREATMENT OF DISEASES ASSOCIATED WITH ALTERED LEVEL OF AMYLOID BETA PEPTIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |