Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924964 | 0.66 | — | — | |
| SCHEMBL5570362 | 0.63 | GAA (0.35) | — | |
| SCHEMBL5565920 | 0.62 | MEN1 (0.39) | ALDH1A1TSHRTRIM24 | |
| SCHEMBL19122298 | 0.58 | — | — | |
| SCHEMBL13183593 | 0.58 | PNMT (0.48) | ALDH1A1TSHR | |
| SCHEMBL1823806 | 0.58 | NOS3 (0.39) | ALDH1A1 | |
| SCHEMBL27398206 | 0.57 | BRD4 (0.43) | BRD4GFERALDH1A1TSHR | |
| SCHEMBL8306539 | 0.57 | MEN1 (0.37) | HSD17B10ALDH1A1TSHRTRIM24 | |
| SCHEMBL10608736 | 0.57 | GSK3A (0.33) | BRD4 | |
| SCHEMBL13827392 | 0.56 | PNMT (0.47) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750719-A2 | TREATMENT OF DISEASES ASSOCIATED WITH ALTERED LEVEL OF AMYLOID BETA PEPTIDES | Boehringer Ingelheim International GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110422-A2 | TREATMENT OF DISEASES ASSOCIATED WITH ALTERED LEVEL OF AMYLOID BETA PEPTIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |