Benzidine

Benzidine

SCHEMBL5570436

Nc1ccc(-c2ccc(N)cc2)cc1.c1ccc2cc3cc4cc5ccccc5cc4cc3cc2c1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
CYP3A4 P08684 5/20 0.68
HSD17B10 Q99714 5/20 0.68
TDP1 Q9NUW8 3/20 0.68
ALOX15 P16050 2/20 0.68
CASP1 P29466 1/20 0.68
CASP7 P55210 1/20 0.68
HBB P68871 1/20 0.68
HIF1A Q16665 1/20 0.68
TAAR1 Q96RJ0 2/20 0.62
TP53 P04637 2/20 0.58
APP P05067 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 3/20 0.48
HPGD P15428 3/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15481474 0.93 CYP3A4 (0.67) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
Anthracene SCHEMBL28259345 0.89 ALDH1A1 (0.74) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
Benzidine SCHEMBL28228458 0.86 HSD17B10 (0.72) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
Benzidine SCHEMBL6528002 0.86 HSD17B10 (0.72) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL29441264 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL28528867 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL6537114 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL28981808 0.85 CYP3A4 (0.65) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL7706106 0.84 PLAU (0.59) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL10422433 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007062527-A1 ORGANIC COLUMNAR THIN FILMS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2007-06-07 WO disclosed