Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 5/20 | 0.89 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.81 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.81 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.76 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.76 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.76 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.64 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | VDR | P11473 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23222857 | 1.00 | SLC10A1 (0.89) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL25791272 | 0.97 | GPBAR1 (0.86) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL23222871 | 0.97 | GPBAR1 (0.86) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL23222893 | 0.97 | GPBAR1 (0.86) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL7998870 | 0.97 | GPBAR1 (0.86) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL19360981 | 0.94 | SLC10A1 (1.00) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL19360976 | 0.94 | SLC10A1 (1.00) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL25943448 | 0.94 | SLC10A1 (1.00) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL19360987 | 0.94 | SLC10A1 (1.00) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 | |
| SCHEMBL19360957 | 0.94 | SLC10A1 (1.00) | SLC10A1GPBAR1SLC10A2ABCC4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853176-A2 | AGENTS AND METHODS FOR ENHANCEMENT OF TRANSDERMAL TRANSPORT | Sontra Medical Corporation (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006091877-A2 | AGENTS AND METHODS FOR ENHANCEMENT OF TRANSDERMAL TRANSPORT | SONTRA MEDICAL CORPORATION (US) | 2006-08-31 | — | — | WO | disclosed |
| US-20060015058-A1 | Agents and methods for enhancement of transdermal transport | KELLOGG SCOTT C | 2006-01-19 | — | — | US | disclosed |