SCHEMBL25943448

C[C@H](CCC(=O)O[C@@H]1CC[C@@]2(C)C(C1)C[C@H](O)[C@H]1C3CC[C@H]([C@H](C)CCC(=O)O[C@@H]4CC[C@@]5(C)C(C4)C[C@H](O)[C@H]4C6CC[C@H]([C@H](C)CCC(=O)NCCS(=O)(=O)O)[C@@]6(C)CC[C@@H]45)[C@@]3(C)CC[C@@H]12)[C@H]1CCC2[C@@H]3[C@@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	SLC10A1	Q14973	7/20	1.00

▸	GPBAR1	Q8TDU6	12/20	0.85

▸	NR1H4	Q96RI1	5/20	0.85

▸	SLC10A2	Q12908	3/20	0.85

▸	ABCC4	O15439	2/20	0.85

▸	ABCB11	O95342	2/20	0.85

▸	ENPP2	Q13822	2/20	0.85

▸	PLA2G1B	P04054	1/20	0.85

▸	VDR	P11473	1/20	0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19360953	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL25943531	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL25946533	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19360987	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19360957	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19360981	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19360976	1.00	SLC10A1 (1.00)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19360964	0.95	SLC10A1 (0.94)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19364456	0.95	SLC10A1 (0.94)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4
SCHEMBL19364448	0.95	SLC10A1 (0.94)	SLC10A1GPBAR1NR1H4SLC10A2ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11701369-B2	Polymeric bile acid derivatives inhibit Hepatitis B and D virus and NTCP transport	HUAHUI HEALTH LTD. (CN)	2023-07-18	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-11701369-B2	Polymeric bile acid derivatives inhibit Hepatitis B and D virus and NTCP transport	SLC10A1, SLC10A2, ABCB11	SLC10A1 1/4885GPBAR1 17/4885NR1H4 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.