Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509074 | 0.81 | DPP4 (0.36) | DPP4 | |
| SCHEMBL28040600 | 0.78 | NOS3 (0.39) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL11539994 | 0.76 | KDM4E (0.38) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL14440005 | 0.76 | DPP4 (0.62) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL16847208 | 0.76 | DPP4 (0.62) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL1335056 | 0.76 | DPP4 (0.62) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL516556 | 0.76 | DPP4 (0.62) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL3762114 | 0.76 | ESR1 (0.33) | — | |
| SCHEMBL8651376 | 0.76 | DPP4 (0.62) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL2196928 | 0.76 | DPP4 (0.62) | KDM4ELMNAHIF1AADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8277749-B2 | Time-temperature indicator based on valence isomerizations | FRESHPOINT HOLDINGS S.A. (CH) | 2012-10-02 | — | — | US | disclosed |
| US-20070172951-A1 | Time-temperature indicator based on valence isomerizations | FRESHPOINT QUALITY ASSURANCE LTD. (IL) | 2007-07-26 | — | — | US | disclosed |