Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575287 | 0.79 | NR1I3 (0.37) | CYP19A1SHBGMBOAT4NR1I3ESR1 | |
| SCHEMBL9692830 | 0.75 | SRD5A2 (0.61) | CYP19A1NR1I3SRD5A2 | |
| SCHEMBL9692825 | 0.75 | SRD5A2 (0.61) | CYP19A1NR1I3SRD5A2 | |
| SCHEMBL1963780 | 0.74 | ESR1 (0.49) | CYP19A1SHBGSRD5A2ESR1AR | |
| SCHEMBL5313823 | 0.74 | SRD5A2 (0.35) | CYP19A1SHBGSRD5A2ESR1AR | |
| SCHEMBL5311339 | 0.72 | CYP19A1 (0.41) | CYP19A1SHBGMBOAT4NR1I3 | |
| SCHEMBL5570855 | 0.72 | CYP19A1 (0.38) | CYP19A1SHBGMBOAT4NR1I3 | |
| SCHEMBL5310140 | 0.70 | CYP19A1 (0.43) | CYP19A1SHBGMBOAT4NR1I3 | |
| SCHEMBL27480646 | 0.70 | ESR1 (0.62) | CYP19A1SRD5A2ESR1ARESR2 | |
| SCHEMBL4944185 | 0.70 | CYP19A1 (0.65) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807118-A2 | STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS | Hollis-Eden Pharmaceuticals Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006110172-A2 | STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS | HOLLIS-EDEN PHARMACEUTICALS.INC. (US) | 2006-10-19 | — | — | WO | disclosed |