Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494151 | 0.78 | CYP19A1 (0.48) | CYP19A1NR1I3SHBGMBOAT4 | |
| SCHEMBL7523457 | 0.74 | CYP19A1 (0.52) | CYP19A1SHBGMBOAT4 | |
| SCHEMBL514461 | 0.72 | CYP19A1 (0.38) | CYP19A1MBOAT4 | |
| SCHEMBL5308811 | 0.72 | CYP19A1 (0.47) | CYP19A1NR1I3SHBGMBOAT4 | |
| SCHEMBL4619438 | 0.72 | CYP19A1 (0.45) | CYP19A1SHBG | |
| SCHEMBL5311339 | 0.71 | CYP19A1 (0.41) | CYP19A1NR1I3SHBGMBOAT4 | |
| SCHEMBL1418483 | 0.71 | CYP19A1 (0.44) | CYP19A1AKR1B10SHBG | |
| SCHEMBL5310137 | 0.71 | CYP19A1 (0.36) | CYP19A1NR1I3SHBGMBOAT4CDK5 | |
| SCHEMBL5570856 | 0.70 | CYP19A1 (0.43) | CYP19A1NR1I3SHBGMBOAT4 | |
| SCHEMBL4448019 | 0.70 | SHBG (0.41) | CYP19A1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030124-A2 | TREATMENT SCREENING METHODS | HOLLIS-EDEN PHARMACEUTICALS, INC (US) | 2007-03-15 | — | — | WO | disclosed |