Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5572536 | 1.00 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL5571631 | 0.88 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL5572047 | 0.78 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL5567762 | 0.78 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL5571996 | 0.78 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL5569263 | 0.78 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL5570144 | 0.76 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL550322 | 0.75 | CYP3A4 (0.41) | HSD11B1 | |
| SCHEMBL550321 | 0.75 | CYP3A4 (0.41) | HSD11B1 | |
| SCHEMBL2700526 | 0.74 | CYP2D6 (0.43) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006053024-A2 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-05-18 | — | — | WO | claimed |