Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571917 | 0.80 | SLC2A1 (0.38) | TDP1NPC1SLC2A1SLC2A4BCHE | |
| SCHEMBL8266780 | 0.79 | RAB9A (0.47) | TSHRMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5572721 | 0.78 | HPGD (0.43) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3186988 | 0.75 | MAPT (0.43) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3206753 | 0.75 | NPC1 (0.43) | TSHRMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8267967 | 0.67 | NPC1 (0.51) | TSHRMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5335198 | 0.65 | RAB9A (0.73) | TSHRKMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL4921429 | 0.63 | CA12 (0.71) | TSHRMEN1KMT2AMAPTNPC1 | |
| SCHEMBL5572839 | 0.63 | MKNK1 (0.40) | ROCK2 | |
| SCHEMBL3206100 | 0.62 | HPGD (0.45) | MEN1KMT2AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |