Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637395 | 0.74 | TSHR (0.53) | POLBKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL11632162 | 0.71 | LMNA (0.56) | POLBKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL11630553 | 0.71 | PHF8 (0.41) | POLBKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL11632856 | 0.67 | MAPK1 (0.46) | POLBSMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL30881051 | 0.66 | MAPK1 (0.51) | CYP2C19KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7594233 | 0.65 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11631680 | 0.65 | MAPK1 (0.58) | POLBKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11632139 | 0.65 | TSHR (0.47) | POLBKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL12523228 | 0.62 | CYP2C19 (0.60) | CYP2C19POLBKDM4ESMN1; SMN2L3MBTL1 | |
| Diprotrizoate SCHEMBL1859049 | 0.61 | LMNA (0.49) | POLBKDM4ESMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830902-A2 | COMBINATION COMPRISING AN AGENT PROVIDING A SIGNAL, AN IMPLANT MATERIAL AND A DRUG | CINVENTION AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006069677-A2 | COMBINATION COMPRISING AN AGENT PROVIDING A SIGNAL, AN IMPLANT MATERIAL AND A DRUG | CINVENTION AG (DE) | 2006-07-06 | — | — | WO | disclosed |