SCHEMBL557186

SCHEMBL557186

O=C(OCCl)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.63
MAPK1 P28482 2/20 0.61
HIF1A Q16665 2/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A3 Q01959 1/20 0.61
KMT2A Q03164 1/20 0.61
LMNA P02545 3/20 0.59
ALDH1A1 P00352 3/20 0.59
F2 P00734 1/20 0.56
TSHR P16473 2/20 0.55
TRPA1 O75762 1/20 0.52
GSK3B P49841 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
GAA P10253 2/20 0.52
KDM4E B2RXH2 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
HPGD P15428 1/20 0.50
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8460879 0.98 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL27541115 0.92 TDP1 (0.55) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11839376 0.89 TDP1 (0.52) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL1243626 0.88 ESR1 (0.50) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL10499568 0.85 SMN1; SMN2 (0.66) TDP1ALDH1A1SMN1; SMN2RAB9AHPGD
SCHEMBL10916834 0.85 KMT2A (0.76) TDP1MAPK1SLC6A2SLC6A3KMT2A
SCHEMBL27588015 0.84 ESR1 (0.46) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL1268976 0.84 MAPT (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL10500401 0.84 TDP1 (0.50) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL1594034 0.83 TDP1 (0.70) TDP1MAPK1HIF1ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 561 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735514-A Preparation method of aminomethylbenzoic acid 江西道仕化学有限公司 2025-04-01 CN claimed
CN-221514505-U Production device of p-chloromethyl benzoic acid 云南衡楚药业有限公司 2024-08-13 CN claimed
CN-221287872-U Processing recovery unit of p-chloromethyl benzoic acid 云南衡楚药业有限公司 2024-07-09 CN claimed
CN-118063472-A Imidazo [3,4-d ] pyrimidine compound and synthetic method and application thereof 河北大学 2024-05-24 CN claimed
CN-106905263-B A kind of preparation method of 4- (4- methyl-1-piperizinylmethyl) benzoic acid dihydrochloride 常州沃腾化工科技有限公司 2019-06-14 CN claimed
CN-107973807-A Triazolobenzothiazole derivative and preparation method and application thereof 唐山学院 2018-05-01 CN claimed
CN-106905263-A A kind of preparation method of 4 (piperizinylmethyl of 4 methyl 1) benzoic acid dihydrochlorides 常州沃腾化工科技有限公司 2017-06-30 CN claimed
CN-106746409-A A kind of efficient disposal of oily sludge agent 郑州北斗七星通讯科技有限公司 2017-05-31 CN claimed
CN-105646204-A Synthesis method of m-chloro methyl benzoic acid tert-butyl ester 杭州福斯特药业有限公司 2016-06-08 CN claimed
CN-103880727-B A kind of halo sulphur compound and its preparation method and application LUZHOU DONGFANG AGROCHEMICAL CO., LTD. (CN) 2016-01-13 CN claimed
CN-101786992-A 2-hydroxymethyl-3,5,6-trimethylpyrazine derivatives, preparation methods and application thereof TIANJIN HANKANG PHARMACEUTICAL 2010-07-28 CN claimed
CN-100575333-C A kind of preparation method of the 4-chloromethyl benzoic acid tert-butyl ester UNIV TONGJI 2009-12-30 CN claimed
CN-100540529-C Azo monomer and polymkeric substance with third order non-linear optical property UNIV SUZHOU (CN) 2009-09-16 CN claimed
CN-101328319-A Water-soluble bridged ring polymethine 3H-indole cyanine dyes ultrasonic synthetic method UNIV YANSHAN (CN) 2008-12-24 CN claimed
CN-101328318-A Water-soluble linear polymethine 3H-indole cyanine dyes ultrasonic synthetic method UNIV YANSHAN (CN) 2008-12-24 CN claimed
CN-101012182-A Azo monomer and polymer with third order non-linear optical property UNIV SOOCHOW (CN) 2007-08-08 CN claimed
CN-1975552-A Third order non-linear optical material monomer, its polymer and production UNIV SUZHOU (CN) 2007-06-06 CN claimed
CN-1907948-A Preparation method of 4-chloromethyl benzoic acid t-butyl ester UNIV TONGJI (CN) 2007-02-07 CN claimed
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US claimed
CN-1183093-A Process for the preparation of stilbenedicarboxylate esters EASTMAN CHEM CO (US) 1998-05-27 CN claimed