SCHEMBL1594034

SCHEMBL1594034

O=C(OCCCl)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.70
LMNA P02545 2/20 0.66
F2 P00734 1/20 0.58
MAPK1 P28482 2/20 0.57
HIF1A Q16665 2/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.53
TSHR P16473 2/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
KDM4E B2RXH2 1/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
TRPA1 O75762 1/20 0.48
GSK3B P49841 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL27549312 0.94 LMNA (0.65) TDP1LMNAF2MAPK1HIF1A
SCHEMBL11233009 0.89 TDP1 (0.54) TDP1LMNAMAPK1SLC6A2KMT2A
SCHEMBL20302724 0.89 TDP1 (0.61) TDP1LMNAF2MAPK1HIF1A
SCHEMBL3180251 0.88 TDP1 (0.78) TDP1LMNAF2MAPK1HIF1A
SCHEMBL137486 0.87 TDP1 (0.83) TDP1LMNAF2MAPK1HIF1A
SCHEMBL3793158 0.86 TDP1 (0.81) TDP1LMNAF2MAPK1HIF1A
SCHEMBL11741530 0.85 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL14673012 0.85 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL14673257 0.85 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL14673582 0.85 TDP1 (0.79) TDP1LMNAMAPK1HIF1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694423-B Catalyst component for ethylene polymerization, preparation method thereof and catalyst for ethylene polymerization 中国石油化工股份有限公司 2021-07-30 CN claimed
EP-4705289-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF Terran Biosciences Inc. (US) 2026-03-11 EP disclosed
EP-4638658-A1 PYROLYSIS OIL PURIFICATION USING SUCCESSIVE EXTRACTIONS SABIC Global Technologies B.V. (NL) 2025-10-29 EP disclosed
CN-119677713-A Processes for preparing benzoates and intermediates thereof 罗卡福拉达有限公司 2025-03-21 CN disclosed
WO-2024226691-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF TERRAN BIOSCIENCES INC. (US) 2024-10-31 WO disclosed
WO-2024134356-A1 PYROLYSIS OIL PURIFICATION USING SUCCESSIVE EXTRACTIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-06-27 WO disclosed
CN-116284778-A Polybenzimidazole with cross-linked structure, high-temperature proton exchange membrane and preparation method thereof 上海空间电源研究所 2023-06-23 CN disclosed
CN-114773215-B Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-09-02 CN disclosed
US-11420963-B2 Rebamipide prodrugs, preparation method and use thereof SAMJIN PHARMACEUTICAL CO., LTD. (KR) 2022-08-23 US disclosed
CN-114773215-A Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-07-22 CN disclosed
US-5789455-A Fluorine-containing hydrocarbon composition ASAHI GLASS COMPANY LTD. (JP) 1998-08-04 US disclosed
CN-1159183-A Di- (2-haloethyl) aminophenyl substituted distamycin derivatives as anticancer and antiviral agents PHARMACIA & UPJOHN SPA (IT) 1997-09-10 CN disclosed
US-5616705-A N-substituted azabicycloheptane derivatives, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1997-04-01 US disclosed
EP-0234045-B1 A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE NIHON NOHYAKU CO., LTD. (JP) 1992-09-02 EP disclosed
US-5021330-A Light sensitive silver halide emulsion layer AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
US-4843068-A INSECTICIDES, MITICIDES, FUNGICIDES NIHON NOHYAKU CO., LTD. (JP) 1989-06-27 US disclosed
EP-0234045-A2 A pyrazole oxime derivative and its production and use NIHON NOHYAKU CO., LTD. (JP) 1987-09-02 EP disclosed
US-4612386-A Process for making esters THE DOW CHEMICAL COMPANY (US) 1986-09-16 US disclosed
US-4568759-A Preparation of epoxides THE DOW CHEMICAL COMPANY (US) 1986-02-04 US disclosed
US-4356295-A COORDINATION CATALYSTS MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1982-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11420963-B2 Rebamipide prodrugs, preparation method and use thereof SI, CYP2A7, MLN TDP1 649/4885LMNA 4782/4885F2 2267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.