Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715738 | 0.90 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL15715191 | 0.89 | KMT2A (0.52) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL23658930 | 0.89 | KMT2A (0.52) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL25798214 | 0.89 | KMT2A (0.52) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL29559391 | 0.85 | KMT2A (0.54) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL25797530 | 0.84 | KMT2A (0.48) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL25797396 | 0.84 | KMT2A (0.45) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL19189841 | 0.83 | MEN1 (0.51) | KMT2AMEN1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL5572402 | 0.82 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL14259711 | 0.81 | KMT2A (0.60) | KMT2AMEN1ALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761549-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002730-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |