Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715738 | 0.91 | KMT2A (0.51) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL9177262 | 0.82 | KMT2A (0.43) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL5572022 | 0.82 | KMT2A (0.50) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL14259711 | 0.79 | KMT2A (0.60) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL7212940 | 0.78 | HPGD (0.41) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL9441197 | 0.78 | MAPT (0.43) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL12377580 | 0.78 | KMT2A (0.43) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL9176311 | 0.77 | KMT2A (0.41) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL18486442 | 0.76 | KMT2A (0.60) | KMT2AMEN1HTTALDH1A1POLB | |
| SCHEMBL8994708 | 0.75 | KMT2A (0.49) | KMT2AMEN1HTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761549-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006002730-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICALLY SUBSTITUTED BIARYLDIPHOSPHINES | LONZA AG (CH) | 2006-01-12 | — | — | WO | disclosed |