Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 4/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892098 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL1891785 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL22262018 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL1894115 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL1890530 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL1892388 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL11063624 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL1899126 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL4282246 | 0.80 | ALDH1A1 (0.34) | ALDH1A1MAPTALOX15MEN1KMT2A | |
| SCHEMBL1891855 | 0.80 | ALDH1A1 (0.34) | ALDH1A1MAPTALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807118-A2 | STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS | Hollis-Eden Pharmaceuticals Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006110172-A2 | STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS | HOLLIS-EDEN PHARMACEUTICALS.INC. (US) | 2006-10-19 | — | — | WO | disclosed |