Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.41 |
| ▸ | CNR2 | P34972 | 15/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234315 | 0.85 | CNR1 (0.38) | CNR1CNR2 | |
| SCHEMBL1234363 | 0.78 | CNR1 (0.35) | CNR1CNR2HCAR3 | |
| SCHEMBL1233723 | 0.74 | GRM2 (0.33) | — | |
| SCHEMBL1233399 | 0.73 | CNR1 (0.42) | CNR1CNR2HCAR3OPRM1 | |
| SCHEMBL1233659 | 0.72 | CNR1 (0.45) | CNR1CNR2PLA2G10 | |
| SCHEMBL10274481 | 0.72 | L3MBTL1 (0.45) | CNR1CNR2PLA2G10 | |
| SCHEMBL1232364 | 0.71 | CNR1 (0.39) | CNR1CNR2PLA2G10HCAR3OPRM1 | |
| SCHEMBL5572245 | 0.70 | CNR1 (0.49) | CNR1CNR2PLA2G10 | |
| SCHEMBL1234011 | 0.68 | PTGER1 (0.38) | CNR1CNR2PLA2G10HCAR3 | |
| SCHEMBL1234228 | 0.68 | CNR1 (0.41) | CNR1CNR2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863809-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107753-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-10-12 | — | — | WO | disclosed |