⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131348 | 1.00 | — | — | |
| SCHEMBL4594779 | 0.86 | — | — | |
| SCHEMBL9665630 | 0.86 | — | — | |
| SCHEMBL9665635 | 0.86 | — | — | |
| SCHEMBL18557969 | 0.84 | — | — | |
| SCHEMBL14639046 | 0.83 | — | — | |
| SCHEMBL16588256 | 0.79 | CYP1A2 (0.62) | — | |
| SCHEMBL971556 | 0.78 | — | — | |
| SCHEMBL7903270 | 0.78 | — | — | |
| SCHEMBL7901480 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280704-B1 | METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER | INST DES SCIENCES ET INDUSTRIES DU VIVANT ET DE LENVIRONNEMENT AGROPARISTECH (FR) | 2019-06-12 | — | — | EP | disclosed |
| US-10183923-B2 | Method for synthesizing a precursor of a single dairy-lactone isomer | INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT—AGROPARIS TECH (FR) | 2019-01-22 | — | — | US | disclosed |
| US-20180072693-A1 | METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER | INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGROPARIS TECH (FR) | 2018-03-15 | — | — | US | disclosed |
| EP-3280704-A1 | METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER | Institut des Sciences et Industries du Vivant et de l'Environnement (FR) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016162646-A1 | METHOD FOR SYNTHESIZING A PRECURSOR OF A SINGLE DAIRY-LACTONE ISOMER | INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGROPARIS TECH (FR) | 2016-10-13 | — | — | WO | disclosed |
| EP-2183250-B1 | NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL INC (US) | 2011-01-12 | — | — | EP | disclosed |
| US-7226906-B2 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| WO-2006023452-A2 | CYCLOSPORIN ANALOGS FOR THE TREATMENT OF IMMUNOREGULATORY DISORDERS AND RESPIRATORY DISEASES | ARRAY BIOPHARMA INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060035821-A1 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA INC. | 2006-02-16 | — | — | US | disclosed |
| US-20060035822-A1 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA INC. | 2006-02-16 | — | — | US | disclosed |