SCHEMBL557244

SCHEMBL557244

NC(=O)CCCCCCCC=C(CCCCCCCCC(N)=O)CCCCCCCC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.52
SOAT1 P35610 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
MEN1 O00255 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
KMT2A Q03164 1/20 0.52
KDM4E B2RXH2 2/20 0.47
CNR1 P21554 1/20 0.39
TBXAS1 P24557 1/20 0.38
MAPT P10636 2/20 0.37
ABCC4 O15439 1/20 0.37
ALDH1A1 P00352 1/20 0.36
ABHD16A O95870 1/20 0.35
EP300 Q09472 1/20 0.34
TERT O14746 2/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9486646 0.90 FAAH (0.69) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL27705359 0.87 FAAH (0.66) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL27958863 0.86 FAAH (0.63) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL1532569 0.85 FAAH (0.79) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL6252970 0.79 FAAH (0.50) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL6821586 0.79 FAAH (0.50) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL232435 0.77 FAAH (0.78) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL462422 0.77 FAAH (0.78) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL2088620 0.77 FAAH (0.78) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL15262896 0.77 FAAH (0.78) FAAHSOAT1CYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5965113-A ANHYROUS GEL-SOLID STICK COMPRISING: ANTIPERSPIRANT ACTIVE; PRIMARY GELLANT; NONPOLAR VOLATILE HYDROCARBON SOLVENT HAVING SPECIFIC SOLUBILITY, VAPOR PRESSURE AND BOILING POINT RANGE; WATER MISCIBLE POLAR SOLVENT; RHEOLOGY, STABILITY, AESTHETICS PROCTER & GAMBLE COMPANY (US) 1999-10-12 US claimed
US-9307821-B2 Stable solid deodorant product and method of manufacturing same Knowlton Development Corporation Inc. (CA) 2016-04-12 US disclosed
US-9308397-B2 Long-wearing cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 2016-04-12 US disclosed
US-9302127-B2 Deodorant with improved endurance and stability Knowlton Development Corporation Inc. (CA) 2016-04-05 US disclosed
US-9247800-B2 Stable solid deodorant product and method of manufacturing same Knowlton Development Corporation Inc (CA) 2016-02-02 US disclosed
US-20150335570-A1 STABLE SOLID DEODORANT PRODUCT AND METHOD OF MANUFACTURING SAME UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT 2015-11-26 US disclosed
US-20140255077-A1 DEODORANT WITH IMPROVED ENDURANCE AND STABILITY KNOWLTON DEVELOPMENT CORP. INC. (CA) 2014-09-11 US disclosed
EP-1827367-B1 Antiperspirant or deodorant compositions UNILEVER PLC (GB) 2014-03-05 EP disclosed
US-20130287470-A1 STABLE SOLID DEODORANT PRODUCT AND METHOD OF MANUFACTURING SAME KNOWLTON DEVELOPMENT CORP. INC. (CA) 2013-10-31 US disclosed
EP-1740151-B1 LONG-WEARING COSMETIC COMPOSITIONS WITH IMPROVED SHINE PROCTER & GAMBLE (US) 2013-10-30 EP disclosed
WO-1998027951-A2 ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS SUBSTANTIALLY FREE OF SELECT POLAR SOLVENTS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027950-A1 ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027949-A1 ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027952-A1 METHODS OF MAKING LOW RESIDUE ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027954-A1 ANTIPERSPIRANT COMPOSITIONS CONTAINING GELLANTS IN THE FORM OF ALKYL AMIDES OF DI- AND TRI-CARBOXYLIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998028008-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING GELLANTS IN THE FORM OF ALKYL AMIDES OF DI- AND TRI-CARBOXYLIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027939-A2 ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS CONTAINING SELECT NUCLEATING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027948-A1 GEL COMPOSITIONS CONTAINING GELLANTS IN THE FORM OF ALKYL AMIDES OF TRI-CARBOXYLIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027955-A1 ANTIPERSPIRANT GEL-SOLID STICK COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998016196-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE PERFORMANCE OF LONG-WEARING COSMETIC PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1998-04-23 WO disclosed