Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740904 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL1297642 | 0.93 | ALDH1A1 (0.53) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL29025199 | 0.86 | MAPT (0.47) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL11637424 | 0.78 | MAPT (0.59) | ALDH1A1MAPTNPC1POLBKCNH3 | |
| SCHEMBL11634715 | 0.78 | MAPT (0.59) | ALDH1A1MAPTNPC1POLBKCNH3 | |
| Phosphoric Acid SCHEMBL28361005 | 0.77 | EPHX1 (0.55) | ALDH1A1MAPTHDAC11HDAC8KCNH3 | |
| SCHEMBL11759173 | 0.76 | ALDH1A1 (0.84) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL4643729 | 0.76 | ALDH1A1 (0.84) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL14968385 | 0.76 | ALDH1A1 (0.84) | ALDH1A1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL4104788 | 0.76 | ALDH1A1 (0.84) | ALDH1A1MAPTHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |