SCHEMBL5573017

SCHEMBL5573017

CN(C)CC#CC=CC#CCN(C)C

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.43
CHRM1 P11229 4/20 0.39
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39
CHRM5 P08912 2/20 0.39
CHRM3 P20309 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14537155 1.00 RAB9A (0.43) RAB9ACHRM1CHRM2CHRM4CHRM5
SCHEMBL5573015 1.00 RAB9A (0.43) RAB9ACHRM1CHRM2CHRM4CHRM5
SCHEMBL14537154 0.87 RAB9A (0.36) RAB9ACHRM1CHRM2CHRM4CHRM5
SCHEMBL14537152 0.84
SCHEMBL11288110 0.80 RAB9A (0.34) RAB9ACHRM1CHRM2CHRM4CHRM5
SCHEMBL16654060 0.77
SCHEMBL22149193 0.77
SCHEMBL1311902 0.75 RAB9A (0.65) RAB9ACHRM1CHRM2CHRM4CHRM5
SCHEMBL5850507 0.67
SCHEMBL8149330 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211603-B1 Enediyne compounds and methods related thereto INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2007-05-01 US disclosed
US-6987132-B1 Enediyne compounds and methods related thereto ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) 2006-01-17 US disclosed
US-6514995-B1 Metal complex is capable of forming a benzenoid diradical under physiological conditions and/or under photothermal conditions ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. 2003-02-04 US disclosed