Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435653 | 0.85 | CRHR1 (0.83) | CRHR1 | |
| SCHEMBL5571426 | 0.84 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL5571412 | 0.81 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL4436255 | 0.79 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL5252276 | 0.79 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL5572010 | 0.78 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL4437572 | 0.77 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL4439051 | 0.77 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL5251387 | 0.77 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL4438962 | 0.77 | CRHR1 (0.81) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253284-B2 | Chemical compounds | GIAXO GROUP LIMITED (GB) | 2007-08-07 | — | — | US | disclosed |
| US-20040171607-A1 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171607-A1 | Chemical compounds | CBR3, CBR1, CYP2B6 | CRHR1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.