Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 15/20 | 0.72 |
| ▸ | F2 | P00734 | 6/20 | 0.72 |
| ▸ | KLK1 | P06870 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 10/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238499 | 0.91 | PRSS1 (0.71) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3240141 | 0.91 | PRSS1 (0.71) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3233206 | 0.90 | PRSS1 (0.70) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3245116 | 0.90 | PRSS1 (0.72) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3245124 | 0.89 | PRSS1 (0.73) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3237996 | 0.86 | PRSS1 (0.69) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3237989 | 0.86 | PRSS1 (0.69) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL7311244 | 0.84 | PRSS1 (1.00) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3245051 | 0.84 | PRSS1 (1.00) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3237730 | 0.84 | PRSS1 (0.71) | PRSS1F2KLK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815865-A1 | THERAPEUTIC AGENT FOR DIABETES COMPRISING PROTEASE-INHIBITING COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-08 | — | — | EP | disclosed |