Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 3/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3007173 | 0.87 | MAPT (0.46) | ALDH1A1POLBTP53 | |
| SCHEMBL3007431 | 0.80 | PTGES (0.49) | PTGESEDNRAMCL1 | |
| SCHEMBL335076 | 0.79 | SMN1; SMN2 (0.50) | KMT2AALDH1A1POLBTP53MEN1 | |
| SCHEMBL3578280 | 0.79 | PTGES (0.53) | PTGESKMT2AALDH1A1EDNRABCL2 | |
| SCHEMBL3016031 | 0.78 | MAPT (0.45) | ALDH1A1POLBTP53 | |
| SCHEMBL333931 | 0.78 | MAPT (0.45) | ALDH1A1POLBTP53 | |
| SCHEMBL3571150 | 0.78 | MAPT (0.45) | ALDH1A1POLBTP53 | |
| SCHEMBL3009481 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1KDM4EPOLBTP53 | |
| SCHEMBL333693 | 0.77 | MAPT (0.43) | PTGESKMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL3012396 | 0.77 | MAPT (0.43) | ALDH1A1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841736-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077367-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |