Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 3/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088536 | 0.85 | EGLN1 (0.62) | CNR2CNR1EGLN1EGLN3 | |
| SCHEMBL2088737 | 0.85 | KDM4E (0.52) | CNR2CNR1KDM4ELMNAMEN1 | |
| SCHEMBL7837453 | 0.83 | CNR2 (0.67) | CNR2CNR1HIF1APDE4APDE4B | |
| SCHEMBL27651859 | 0.75 | CNR2 (0.55) | CNR2CNR1PDE4APDE4BPDE4C | |
| SCHEMBL7837905 | 0.75 | CNR2 (0.58) | CNR2CNR1KDM4EMEN1KMT2A | |
| SCHEMBL7833529 | 0.75 | EGLN1 (0.56) | CNR2CNR1FEN1ERCC5KDM4E | |
| SCHEMBL4167289 | 0.75 | KDM4E (0.55) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11488105 | 0.74 | CNR1 (0.47) | CNR2CNR1FEN1ERCC5KDM4E | |
| SCHEMBL2087820 | 0.74 | EGLN3 (0.59) | EGLN1LMNAMEN1KMT2AEGLN3 | |
| SCHEMBL24002959 | 0.73 | KDM4E (0.49) | CNR2CNR1FEN1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213335-A1 | Prolyl Hydroxylase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213335-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN2, EGLN3 | CNR2 2524/4885CNR1 2493/4885FEN1 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.