Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833351 | 0.87 | EGLN1 (0.54) | EGLN1KDM4EALDH1A1L3MBTL1CNR2 | |
| SCHEMBL1522997 | 0.86 | ALDH1A1 (0.58) | EGLN1KDM4EKDM4AALDH1A1HPGD | |
| SCHEMBL7837453 | 0.81 | CNR2 (0.67) | EGLN1CNR2CNR1HIF1A | |
| SCHEMBL1523333 | 0.80 | KDM4E (0.59) | EGLN1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7837905 | 0.79 | CNR2 (0.58) | KDM4EALDH1A1L3MBTL1CNR2CNR1 | |
| SCHEMBL11488105 | 0.76 | CNR1 (0.47) | EGLN1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL4553613 | 0.76 | EGLN1 (0.76) | EGLN1CNR2CNR1 | |
| SCHEMBL5574170 | 0.75 | CNR2 (0.48) | EGLN1KDM4EALDH1A1TSHRHTT | |
| SCHEMBL4553615 | 0.75 | EGLN1 (0.75) | EGLN1L3MBTL1CNR2CNR1 | |
| SCHEMBL4849877 | 0.75 | ALDH1A1 (0.53) | EGLN1KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784622-B1 | NAPHTHYRIDINONE DERIVATIVES | KNOLL GMBH (DE) | 2001-11-21 | — | — | EP | claimed |