Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080279 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2AALOX5 | |
| SCHEMBL4077733 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AALOX5 | |
| SCHEMBL5574390 | 0.78 | MAPT (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AALOX5 | |
| SCHEMBL27697595 | 0.72 | KMT2A (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AOPRK1 | |
| SCHEMBL28771821 | 0.69 | KMT2A (0.48) | ALDH1A1MEN1KMT2AOPRK1MAPT | |
| SCHEMBL27717957 | 0.69 | KMT2A (0.47) | ALDH1A1MEN1KMT2AOPRK1MAPT | |
| SCHEMBL4081988 | 0.68 | PTGER4 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2AALOX5 | |
| SCHEMBL4077453 | 0.68 | KMT2A (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4084927 | 0.67 | PTGER4 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4077776 | 0.66 | PTGER4 (0.55) | ALDH1A1SMN1; SMN2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |