Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26337669 | 0.82 | CXCR4 (0.52) | CXCR4 | |
| SCHEMBL10367296 | 0.80 | CXCR4 (0.51) | CXCR4 | |
| SCHEMBL2084232 | 0.78 | CXCR4 (1.00) | CXCR4 | |
| SCHEMBL5058356 | 0.78 | CXCR4 (1.00) | CXCR4 | |
| SCHEMBL2084234 | 0.78 | CXCR4 (1.00) | CXCR4 | |
| SCHEMBL4219056 | 0.77 | CXCR4 (0.94) | CXCR4 | |
| SCHEMBL2084765 | 0.74 | CXCR4 (0.56) | CXCR4 | |
| SCHEMBL2084588 | 0.74 | CXCR4 (0.72) | CXCR4 | |
| SCHEMBL1698247 | 0.73 | CXCR4 (0.40) | CXCR4 | |
| SCHEMBL4350910 | 0.73 | CXCR4 (0.42) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291631-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
| US-20040209921-A1 | CXCR4 chemokine receptor binding comounds | ANORMED CORPORATION (CA) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209921-A1 | CXCR4 chemokine receptor binding comounds | CXCR4, CXCR1, CXCR3 | CXCR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.