Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 5/20 | 0.43 |
| ▸ | F3 | P13726 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10409030 | 0.85 | POLB (0.57) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD | |
| SCHEMBL21685881 | 0.81 | POLB (0.67) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD | |
| SCHEMBL5574642 | 0.78 | HDAC8 (0.59) | ALDH1A1HSD17B10HPGDMAPK1TDP1 | |
| SCHEMBL5574643 | 0.78 | HDAC8 (0.59) | ALDH1A1HSD17B10HPGDMAPK1TDP1 | |
| SCHEMBL21959256 | 0.78 | HDAC8 (0.59) | ALDH1A1HSD17B10HPGDMAPK1TDP1 | |
| SCHEMBL7395617 | 0.75 | TDP1 (0.54) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD | |
| SCHEMBL8895234 | 0.74 | TDP1 (0.50) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD | |
| SCHEMBL13455143 | 0.74 | TDP1 (0.53) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD | |
| Linoleic Acid SCHEMBL27850562 | 0.74 | PPARG (0.72) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD | |
| SCHEMBL5277177 | 0.73 | TDP1 (0.56) | ALDH1A1HSD17B10KDM4ECYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755684-B1 | ALBUMIN-BINDING CONJUGATES COMPRISING A FATTY ACID AND PEG | UCB BIOPHARMA SPRL (BE) | 2016-08-31 | — | — | EP | disclosed |
| EP-1755684-A2 | ALBUMIN-BINDING CONJUGATES COMPRISING A FATTY ACID AND PEG | Celltech R&D Limited (GB) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005117984-A2 | ALBUMIN-BINDING CONJUGATES COMPRISING A FATTY ACID AND PEG | CELLTECH R & D LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |