SCHEMBL5574686

SCHEMBL5574686

CCCCCCCCCCCCCC(N=C=O)[Si](OCC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
SMPD1 P17405 3/20 0.32
ACE2 Q9BYF1 1/20 0.32
OPRM1 P35372 1/20 0.31
FDPS P14324 4/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
GPR84 Q9NQS5 3/20 0.31
FFAR1 O14842 1/20 0.31
TP53 P04637 1/20 0.30
LCK P06239 1/20 0.30
PPARD Q03181 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394592 0.98 OPRM1 (0.32) MAPTOPRM1TP53
SCHEMBL393579 0.93
SCHEMBL200003 0.86
SCHEMBL5575270 0.85 ZDHHC7 (0.35) MAPTSMPD1ACE2FDPSZDHHC7
SCHEMBL393428 0.83 OPRM1 (0.31) MAPTOPRM1TP53
SCHEMBL395349 0.83 ZDHHC7 (0.33) MAPTSMPD1ACE2ZDHHC7
SCHEMBL394490 0.82 OPRM1 (0.31) OPRM1
SCHEMBL185114 0.78
SCHEMBL4667950 0.78
SCHEMBL29062522 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007019478-A2 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-02-15 WO disclosed