Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578887 | 0.85 | ALDH1A1 (0.72) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL11863719 | 0.85 | ALDH1A1 (0.45) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL14865008 | 0.84 | ALDH1A1 (0.70) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL557758 | 0.82 | ALDH1A1 (0.68) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL13433476 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL20520533 | 0.79 | ALDH1A1 (0.63) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL12728436 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL25625650 | 0.76 | GAA (0.48) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL10021922 | 0.76 | ALDH1A1 (0.70) | ALDH1A1CYP2D6GAAMGAMSI | |
| SCHEMBL3412115 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP2D6GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417151-B1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | UNIV GRENOBLE 1 (FR) | 2016-09-14 | — | — | EP | disclosed |
| US-9133237-B2 | Cyclic peptides with an anti-parasitic activity | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2015-09-15 | — | — | US | disclosed |
| US-9133237-B2 | Cyclic peptides with an anti-parasitic activity | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2015-09-15 | — | — | US | disclosed |
| US-9133237-B2 | Cyclic peptides with an anti-parasitic activity | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2015-09-15 | — | — | US | disclosed |
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-09 | — | — | US | disclosed |
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-09 | — | — | US | disclosed |
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010116085-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) (FR) | 2010-10-14 | — | — | WO | disclosed |
| US-4034090-A | ANTIBACTERIAL | RHONE-POULENC INDUSTRIES (FR) | 1977-07-05 | — | — | US | disclosed |
| US-3969342-A | BACTERICIDE | RHONE-POULENC INDUSTRIES (FR) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034593-A1 | CYCLIC PEPTIDES WITH AN ANTI-PARASITIC ACTIVITY | VIP, NGLY1, QPCT | ALDH1A1 4453/4885CYP2D6 4293/4885GAA 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.