Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.77 |
| ▸ | PPARG | P37231 | 7/20 | 0.77 |
| ▸ | PPARD | Q03181 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TLR2 | O60603 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL5183856 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL5874969 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL4910739 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8469342 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL21145320 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL10533983 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL5874166 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL5875370 | 0.98 | AKR1B1 (0.76) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL27885575 | 0.95 | AKR1B1 (0.73) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL27546331 | 0.93 | AKR1B1 (0.70) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160199027-A1 | ULTRASOUND PROBE COUPLERS AND RELATED METHODS | SCULLY, CASEY K. | 2016-07-14 | — | — | US | claimed |
| CN-102337020-B | Anti-static polyurethane elastomer material used under ultralow humidity condition and preparation method thereof | SUZHOU XINLUN CLEAN TECHNOLOGY CO LTD | 2013-03-20 | — | — | CN | claimed |
| CN-102337020-A | Anti-static polyurethane elastomer material used under ultralow humidity condition and preparation method thereof | SUZHOU XINLUN CLEAN TECHNOLOGY CO LTD | 2012-02-01 | — | — | CN | claimed |
| US-5863524-A | INCLUDING A POLYAMINE CLARIFIER WITH AN ALKALI METAL BICARBONATE OR CARBONATE, A POLYHYDRIC ALCOHOL, A FATTY ACID SALT AND WATER; STABILITY; FEEL | CHURCH & DWIGHT CO., INC. (US) | 1999-01-26 | — | — | US | claimed |
| EP-3538225-B1 | ALUMINUM-FREE ANTIPERSPIRANT/DEODORANT COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2026-04-01 | — | — | EP | disclosed |
| US-12398232-B2 | HFO containing PU formulation | BASF SE (DE) | 2025-08-26 | — | — | US | disclosed |
| US-20240325266-A1 | Personal Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2024-10-03 | — | — | US | disclosed |
| CN-110603275-B | Dispersion of magnetizable particles in polyol, preparation and use thereof | 巴斯夫欧洲公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-110072508-B | Aluminum-free antiperspirant/deodorant compositions | 高露洁-棕榄公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11147755-B2 | Aluminum-free antiperspirant / deodorant compositions | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-19 | — | — | US | disclosed |
| US-10980510-B2 | Ultrasound probe couplers and related methods | Scully, Casey K. (US) | 2021-04-20 | — | — | US | disclosed |
| EP-3538054-B1 | ALUMINUM-FREE ANTIPERSPIRANT/DEODORANT COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-0430624-A1 | Gear oils and additives therefor | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0428393-A1 | Gear oils and additives therefor | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4383089-A | Process for the production of polyepoxy silicate resin | BLOUNT DAVID H | 1983-05-10 | — | — | US | disclosed |
| US-4376173-A | LIGNIN, CELLULOSE, POLYURETHANE FOAM, POLYISOCYANATE | BLOUNT DAVID H | 1983-03-08 | — | — | US | disclosed |
| US-4367326-A | Process for the production of polyepoxy silicate resins | DORSEY & WHITNEY LLP | 1983-01-04 | — | — | US | disclosed |
| EP-0055256-A1 | PROCESS FOR THE PRODUCTION FOR POLYISOCYANATE-POLYESTER-SILICATE PLASTIC | BLOUNT, David H. (US) | 1982-07-07 | — | — | EP | disclosed |
| WO-1982000034-A1 | PROCESS FOR THE PRODUCTION FOR POLYISOCYANATE-POLYESTER-SILICATE PLASTIC | BLOUNT D | 1982-01-07 | — | — | WO | disclosed |
| US-4211848-A | UNSATURATED POLYESTER, WATER CONTAINING OXIDATED SILICON COMPOUND | BLOUNT DAVID H (US) | 1980-07-08 | — | — | US | disclosed |