SCHEMBL5575236

SCHEMBL5575236

CC1(N)NCCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.46
HTR2A P28223 2/20 0.41
HTR2C P28335 1/20 0.40
MAOB P27338 2/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PRCP P42785 1/20 0.37
PNMT P11086 1/20 0.36
CD44 P16070 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674239 0.80 HTR2A (0.43) KDM1AHTR2AHTR2CMAOBPNMT
SCHEMBL327743 0.80 HTR2A (0.43) KDM1AHTR2AHTR2CMAOBPNMT
Hydrochloric Acid SCHEMBL1952104 0.78 HTR2A (0.42) KDM1AHTR2AHTR2CMAOBPNMT
SCHEMBL24124810 0.77 HTR2A (0.41) KDM1AHTR2AHTR2CMAOBMEN1
SCHEMBL29705936 0.77 HTR2A (0.41) KDM1AHTR2AHTR2CMAOBMEN1
SCHEMBL28831342 0.76 KDM1A (0.41) KDM1AHTR2AHTR2CMAOBMEN1
SCHEMBL9374419 0.74 CYP3A4 (0.42) KDM1AHTR2AMEN1KMT2APRCP
SCHEMBL19223430 0.74 PRCP (0.39) KDM1AHTR2AHTR2CMAOBMEN1
SCHEMBL8819738 0.74 PRCP (0.39) KDM1AHTR2AHTR2CMAOBMEN1
SCHEMBL8818780 0.74 HTR2A (0.39) KDM1AHTR2AHTR2CMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183273-B2 Chemokine receptor binding heterocyclic compounds ANORMED, INC. (CA) 2007-02-27 US disclosed