Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674239 | 1.00 | HTR2A (0.43) | HTR2AHTR2CKDM1APNMTCD44 | |
| Hydrochloric Acid SCHEMBL1952104 | 0.98 | HTR2A (0.42) | HTR2AHTR2CKDM1APNMTCD44 | |
| SCHEMBL26327444 | 0.88 | KDM1A (0.46) | HTR2AKDM1A | |
| SCHEMBL5575236 | 0.80 | KDM1A (0.46) | HTR2AHTR2CKDM1APNMTCD44 | |
| SCHEMBL29705936 | 0.80 | HTR2A (0.41) | HTR2AHTR2CKDM1APNMTCD44 | |
| SCHEMBL24124810 | 0.80 | HTR2A (0.41) | HTR2AHTR2CKDM1APNMTCD44 | |
| SCHEMBL3542185 | 0.78 | ALDH1A1 (0.43) | HTR2A | |
| SCHEMBL9374419 | 0.77 | CYP3A4 (0.42) | HTR2AKDM1A | |
| SCHEMBL8818780 | 0.77 | HTR2A (0.39) | HTR2AHTR2CKDM1APNMTCD44 | |
| SCHEMBL19223430 | 0.77 | PRCP (0.39) | HTR2AHTR2CKDM1APNMTCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230350294-A1 | Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-20220380314-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL R&D INVEST S A (PT) | 2022-12-01 | — | — | US | disclosed |
| CN-114901652-A | Substituted saturated and unsaturated N-heterocyclic carboxamides and related compounds for the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-4031540-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |
| US-20220154232-A1 | Benzylisoquinoline Alkaloids (BIA) Producing Microbes, and Methods of Making and Using the Same | HERCULES CAPITAL, INC., AS AGENT | 2022-05-19 | — | — | US | disclosed |
| US-11214819-B2 | Benzylisoquinoline alkaloids (BIA) producing microbes, and methods of making and using the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| EP-3865580-A1 | BENZYLISOQUINOLINE ALKALOIDS (BIA) PRODUCING MICROBES, AND METHODS OF MAKING AND USING THE SAME | The Board of Trustees of the Leland Stanford Junior University (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20210189445-A1 | Benzylisoquinoline Alkaloids (BIA) Producing Microbes, and Methods of Making and Using the Same | HERCULES CAPITAL, INC., AS AGENT | 2021-06-24 | — | — | US | disclosed |
| US-10988787-B2 | Benzylisoquinoline alkaloids (BIA) producing microbes, and methods of making and using the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-04-27 | — | — | US | disclosed |
| CN-1255917-A | Anti-convulsant isoquinolyl-benzamide derivatives | SMITHKLINE BEECHAM PLC (GB) | 2000-06-07 | — | — | CN | disclosed |
| CN-1046713-C | Tetrahydroisoquinoline compounds, pharmaceutical compositions containing them, and their preparation and use | KNORR CO LTD (GB) | 1999-11-24 | — | — | CN | disclosed |
| CN-1212020-A | Method and compositions for analyzing nucleic acid molecules utilizing sizing techniques | RAPIGENE INC (US) | 1999-03-24 | — | — | CN | disclosed |
| CN-1212021-A | Method and compositions for determining sequence of nucleic acid molecules | RAPIGENE INC (US) | 1999-03-24 | — | — | CN | disclosed |
| CN-1212019-A | Methods and compositions for detecting ligand pair binding using non-fluorescent labels | RAPIGENE INC (US) | 1999-03-24 | — | — | CN | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |
| WO-1997036588-A2 | USE OF 1,1-DIALKYL-1,2,3,4-TETRAHYDROISOQUINOLINES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF PSYCHOSIS AND PAIN | LEDERLE (JAPAN), LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |
| CN-1128992-A | Therapeutic agents | KNORR CO LTD (DE) | 1996-08-14 | — | — | CN | disclosed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380314-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GBA2, CLN6 | HTR2A 828/4885HTR2C 853/4885KDM1A 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.