Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124275 | 0.94 | ALDH1A1 (0.67) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL30716581 | 0.94 | ALDH1A1 (0.67) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL28454845 | 0.94 | ALDH1A1 (0.66) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL3911167 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL27519361 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL29828588 | 0.83 | ALDH1A1 (0.78) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL4291079 | 0.83 | ALDH1A1 (0.78) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL30766153 | 0.83 | TSHR (0.50) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL7266974 | 0.80 | UTS2R (0.40) | ALDH1A1CYP3A4CA2TSHRMAPK1 | |
| Diethylamine SCHEMBL2931167 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CA2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7249723-B2 | Organic solvent dispersed nano-talc slurry | NGX, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| WO-2007024252-A2 | ORGANIC SOLVENT DISPERSED NANO-TALC SLURRY | NANOMAT, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060086837-A1 | Dry milling talc powder, mixing the dry-milled nano-talc powder with an organic solvent andwet milling the nano-talc-solvent mix | NGX, INC. | 2006-04-27 | — | — | US | disclosed |