Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072717 | 0.93 | TSHR (0.68) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27545209 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27825328 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28450048 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL20503336 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27821802 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27880352 | 0.89 | TSHR (0.57) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL10622538 | 0.89 | TSHR (0.57) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28126578 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL15264948 | 0.87 | TSHR (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7249723-B2 | Organic solvent dispersed nano-talc slurry | NGX, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| WO-2007024252-A2 | ORGANIC SOLVENT DISPERSED NANO-TALC SLURRY | NANOMAT, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060086837-A1 | Dry milling talc powder, mixing the dry-milled nano-talc powder with an organic solvent andwet milling the nano-talc-solvent mix | NGX, INC. | 2006-04-27 | — | — | US | disclosed |